Mfundo za kujambula kwa photoacoustic

Mfundo za kujambula kwa photoacoustic

Photoacoustic Imaging (PAI) ndi njira yojambula zamankhwala yomwe imaphatikizaopticsndi ma acoustics kuti apange ma ultrasonic signals pogwiritsa ntchito kugwirizana kwakuwalandi minofu kuti mupeze zithunzi za minofu yokhazikika. Amagwiritsidwa ntchito kwambiri m'magawo azachipatala, makamaka pozindikira chotupa, kujambula kwa mitsempha, kujambula pakhungu ndi zina.

Mfundo:
1. Kuwala kowala ndi kukulitsa kutentha: - Kujambula kwa Photoacoustic kumagwiritsa ntchito kutentha komwe kumapangidwa ndi kuyamwa kwa kuwala. Mamolekyu a pigment omwe ali mu minofu (monga hemoglobin, melanin) amamwa ma photon (nthawi zambiri amakhala pafupi ndi kuwala kwa infrared), omwe amasandulika kukhala mphamvu ya kutentha, zomwe zimapangitsa kutentha kwaderalo kukwera.
2. Kuwonjezeka kwa kutentha kumayambitsa ultrasound: - Kutentha kwa kutentha kumabweretsa kukula kwa minofu, yomwe imapanga mafunde amphamvu (ie ultrasound).
3. Akupanga kuzindikira: – The kwaiye akupanga mafunde kufalikira mkati minofu, ndipo zizindikiro kenako analandira ndi olembedwa ndi akupanga masensa (monga akupanga probes).
4. Image kumangidwanso: anasonkhanitsidwa akupanga chizindikiro ndi masamu ndi kukonzedwa kuti amangenso dongosolo ndi ntchito fano la minofu, amene angapereke kuwala mayamwidwe makhalidwe a minofu. Ubwino wa kujambula zithunzi: Kusiyanitsa kwakukulu: Kujambula zithunzi kumadalira maonekedwe a kuwala kwa minofu, ndipo minofu yosiyana (monga magazi, mafuta, minofu, ndi zina zotero) imakhala ndi luso losiyanasiyana lotengera kuwala, kotero imatha kupereka zithunzi zosiyana kwambiri. Kusamvana kwakukulu: Pogwiritsa ntchito mawonekedwe apamwamba a ultrasound, kujambula kwa photoacoustic kumatha kukwaniritsa kulondola kwa millimeter kapena ngakhale submillimeter. Zosasokoneza: Kujambula kwa Photoacoustic sikusokoneza, kuwala ndi phokoso sikungawononge minofu, yoyenera kwambiri kuti munthu adziwe zachipatala. Kuthekera kwa kujambula mozama: Poyerekeza ndi kujambula kwachikhalidwe, kujambula kwazithunzi kumatha kulowa masentimita angapo pansi pa khungu, komwe kuli koyenera kujambula minofu yakuya.

Ntchito:
1. Kujambula kwa mitsempha: - Kujambula kwa Photoacoustic kumatha kudziwa momwe hemoglobini imayamwa kuwala m'magazi, kotero imatha kuwonetsa bwino momwe mitsempha yamagazi imapangidwira komanso momwe mitsempha yamagazi imayendera poyang'anira microcirculation ndi kuweruza matenda.
2. Kuzindikira chotupa: - Angiogenesis mu minyewa ya chotupa nthawi zambiri imakhala yochuluka kwambiri, ndipo kujambula kwazithunzi kungathandize kuzindikira msanga zotupazo pozindikira zolakwika m'mitsempha.
3. Kujambula kogwira ntchito: - Kujambula kwa Photoacoustic kungathe kuyesa mpweya wa okosijeni wa minyewa pozindikira kuchuluka kwa oxygenation ndi deoxyhemoglobin mu minyewa, yomwe ili yofunika kwambiri pakuwunika magwiridwe antchito a matenda monga khansa ndi matenda amtima.
4. Kujambula pakhungu: - Chifukwa kujambula kwazithunzi kumakhudzidwa kwambiri ndi minofu yapakhungu, ndikoyenera kuzindikira msanga khansa yapakhungu ndikuwunika zolakwika zapakhungu.
5. Kujambula kwaubongo: Kujambula zithunzi kungathe kupeza chidziwitso cha kayendedwe ka magazi mu ubongo m'njira yosasokoneza pophunzira matenda a ubongo monga sitiroko ndi khunyu.

Zovuta ndi mayendedwe a chitukuko cha kujambula kwa Photoacoustic:
Gwero la kuwalakusankha: Kuwala kolowera kwa mafunde osiyanasiyana ndi kosiyana, momwe mungasankhire mayendedwe oyenera a wavelength ndi kuzama kolowera ndizovuta. Kukonzekera kwa ma Signal: Kupeza ndi kukonza ma siginecha akupanga kumafuna ma aligorivimu othamanga komanso olondola, komanso kupanga ukadaulo womanganso zithunzi ndikofunikira. Kujambula kwa Multimodal: Kujambula kwazithunzi kumatha kuphatikizidwa ndi njira zina zojambulira (monga MRI, CT, imaging ultrasound) kuti apereke zambiri zamoyo zambiri.

Kujambula kwa Photoacoustic ndi teknoloji yatsopano komanso yogwira ntchito yambiri ya biomedical imaging, yomwe ili ndi mawonekedwe a kusiyana kwakukulu, kusamvana kwakukulu komanso kosasokoneza. Ndi chitukuko chaukadaulo, kujambula kwazithunzi kumakhala ndi mwayi wogwiritsa ntchito kwambiri pakuzindikira zachipatala, kafukufuku woyambira wa biology, chitukuko cha mankhwala ndi magawo ena.