Gulu la ku America likupereka njira yatsopano yosinthira ma microdisk lasers

Gulu lofufuza logwirizana kuchokera ku Harvard Medical School (HMS) ndi MIT General Hospital lati lakwanitsa kusintha momwe laser ya microdisk imagwirira ntchito pogwiritsa ntchito njira ya PEC etching, zomwe zimapangitsa kuti pakhale njira yatsopano yopangira nanophotonics ndi biomedicine "yothandiza."

(Zotuluka za laser ya microdisk zitha kusinthidwa pogwiritsa ntchito njira ya PEC etching)

M'minda yananophotonicsndi biomedicine, microdiskma laserndipo ma laser a nanodisk akhala odalirikamagwero a kuwalandi ma probe. Mu ntchito zingapo monga kulumikizana kwa ma photonic pa chip, bioimaging pa chip, biochemical sensing, ndi quantum photon information processing, amafunika kukwaniritsa kutulutsa kwa laser podziwa kutalika kwa mafunde ndi kulondola kwa band yopapatiza kwambiri. Komabe, zimakhala zovuta kupanga ma microdisk ndi nanodisk lasers a kutalika kolondola kumeneku pamlingo waukulu. Njira zamakono zopangira ma nano zimabweretsa kusasinthika kwa dayamita ya disc, zomwe zimapangitsa kuti zikhale zovuta kupeza kutalika kwa mafunde komwe kumayikidwa pokonza ndi kupanga ma laser. Tsopano, gulu la ofufuza ochokera ku Harvard Medical School ndi Massachusetts General Hospital's Wellman Center forMankhwala a Optoelectronicyapanga njira yatsopano yopangira ma optochemical (PEC) yomwe imathandiza kusintha bwino kutalika kwa mafunde a laser ya microdisk laser ndi kulondola kwa subnanometer. Ntchitoyi yafalitsidwa mu magazini ya Advanced Photonics.

Kujambula kwa Photochemical
Malinga ndi malipoti, njira yatsopano ya gululi imalola kupanga ma micro-disk lasers ndi nanodisk laser arrays okhala ndi ma wavelengths olondola komanso okonzedweratu. Chinsinsi cha kupita patsogolo kumeneku ndikugwiritsa ntchito PEC etching, yomwe imapereka njira yothandiza komanso yowonjezereka yowongolera ma wavelengths a microdisc laser. Mu zotsatira zomwe zili pamwambapa, gululi linapeza bwino indium Gallium arsenide phosphating microdisks yokutidwa ndi silica pa kapangidwe ka indium phosphide column. Kenako anasintha ma wavelengths a laser a ma microdisks awa kukhala ndi mtengo wotsimikizika mwa kuchita photochemical etching mu yankho lochepetsedwa la sulfuric acid.
Anafufuzanso njira ndi mphamvu za ma etchings enieni a photochemical (PEC). Pomaliza, anasamutsa microdisk array yokonzedwa ndi wavelength kupita ku polydimethylsiloxane substrate kuti apange tinthu ta laser tokha tokha tokhala ndi ma wavelength osiyanasiyana a laser. Microdisk yomwe imachokera ikuwonetsa bandwidth ya ultra-wideband ya laser emission, ndilaserpa nsanamira yosakwana 0.6 nm ndi tinthu tomwe tapatuka tosakwana 1.5 nm.

Kutsegula chitseko cha ntchito za sayansi ya zamankhwala
Zotsatirazi zimatsegula chitseko cha ma nanophotonics ambiri atsopano ndi ntchito za biomedical. Mwachitsanzo, ma microdisk lasers odziyimira pawokha amatha kugwira ntchito ngati ma barcode a physico-optical a zitsanzo zamoyo zosiyanasiyana, zomwe zimathandiza kulemba mitundu inayake ya maselo ndi kuyang'ana mamolekyu enaake mu kusanthula kwa multiplex. Kulemba kwa mtundu wa maselo kumachitika pakadali pano pogwiritsa ntchito ma biomarker odziwika bwino, monga organic fluorophores, ma quantum dots, ndi mikanda ya fluorescent, yomwe ili ndi mipata yayikulu yotulutsa mpweya. Chifukwa chake, mitundu yochepa chabe ya maselo ndi yomwe ingalemberedwe nthawi imodzi. Mosiyana ndi zimenezi, kuwala kwa ultra-narrow band komwe kumatuluka mu microdisk laser kudzatha kuzindikira mitundu yambiri ya maselo nthawi imodzi.
Gululi linayesa ndikuwonetsa bwino tinthu tating'onoting'ono ta laser tomwe tinasinthidwa bwino ngati ma biomarker, pogwiritsa ntchito zilembo za maselo abwinobwino a epithelial a m'mawere a MCF10A. Ndi kutulutsa kwawo kwa ultra-wideband, ma laser awa akhoza kusintha biosensing, pogwiritsa ntchito njira zodziwika bwino za biomedical ndi optical monga cytodynamic imaging, flow cytometry, ndi multi-omics analysis. Ukadaulo wozikidwa pa PEC etching umasonyeza kupita patsogolo kwakukulu mu ma microdisk lasers. Kukula kwa njirayo, komanso kulondola kwake kwa subnanometer, kumatsegula mwayi watsopano wogwiritsa ntchito ma lasers ambiri mu nanophotonics ndi zida za biomedical, komanso ma barcode a maselo enaake ndi mamolekyulu osanthula.