Gulu lophatikizana lofufuza kuchokera ku Harvard Medical School (HMS) ndi MIT General Hospital lati akwanitsa kukonza zotulutsa laser microdisk pogwiritsa ntchito njira ya PEC etching, kupanga gwero latsopano la nanophotonics ndi biomedicine "lolonjeza."
(Kutulutsa kwa laser microdisk kumatha kusinthidwa ndi njira ya PEC etching)
M'minda yananophotonicsndi biomedicine, microdisklasersndipo ma nanodisk lasers akhala akulonjezamagwero a kuwalandi probes. M'mapulogalamu angapo monga on-chip photonic communication, on-chip bioimaging, biochemical sensing, ndi quantum photon information processing, amayenera kukwaniritsa zotsatira za laser pozindikira kulondola kwa bandength ndi ultra-narrow band. Komabe, zimakhalabe zovuta kupanga ma microdisk ndi ma lasers a nanodisk a kutalika kwake komweku pamlingo waukulu. Njira zamakono za nanofabrication zimabweretsa kusasinthika kwa disc diameter, zomwe zimapangitsa kuti zikhale zovuta kupeza kutalika kwa kutalika kwa laser mass processing ndi kupanga. Tsopano, gulu la ofufuza ochokera ku Harvard Medical School ndi Wellman Center ya Massachusetts General Hospital forOptoelectronic Medicinewapanga njira yaukadaulo ya optochemical (PEC) etching yomwe imathandizira kuwongolera bwino kutalika kwa laser ya microdisk laser ndi kulondola kwa subnanometer. Ntchitoyi idasindikizidwa mu nyuzipepala ya Advanced Photonics.
Photochemical etching
Malinga ndi malipoti, njira yatsopano ya gululi imathandizira kupanga ma lasers a micro-disk ndi ma nanodisk laser arrays okhala ndi mafunde olondola, odziwikiratu. Chinsinsi cha kupambana kumeneku ndi kugwiritsa ntchito PEC etching, yomwe imapereka njira yabwino komanso yowongoka yowongola bwino kutalika kwa mafunde a laser microdisc. Muzotsatira zomwe zili pamwambazi, gululo linapeza bwino ma microdisks a indium Gallium arsenide phosphating okhala ndi silika pa indium phosphide column. Kenako anasintha kutalika kwa mafunde a laser a ma microdisk amenewa ndendende ku mtengo wotsimikizirika popanga photochemical etching mu njira yosungunuka ya sulfuric acid.
Adafufuzanso momwe zimagwirira ntchito komanso kusinthika kwa ma etchings apadera a photochemical (PEC). Pomaliza, adasamutsira gulu la ma microdisk a wavelength-tuned pa polydimethylsiloxane gawo lapansi kuti apange tinthu tating'ono ta laser tokhala ndi mafunde osiyanasiyana a laser. Ma microdisk omwe amachokera akuwonetsa bandwidth yowonjezereka ya laser emission, ndilaserpa ndime zosakwana 0,6 nm ndi akutali tinthu zosakwana 1.5 nm.
Kutsegula chitseko cha biomedical applications
Chotsatirachi chimatsegula chitseko cha ma nanophotonics atsopano ndi ntchito zachipatala. Mwachitsanzo, ma lasers oima pawokha a microdisk amatha kukhala ngati ma barcode a physico-optical barcode of heterogeneous biological samples, zomwe zimatheketsa kulemba mitundu yeniyeni ya maselo ndi kulunjika kwa mamolekyu enaake pakuwunika kwa ma multiplex. monga organic fluorophores, madontho a quantum, ndi mikanda ya fulorosenti, yomwe imakhala ndi mizere yambiri yotulutsa. Choncho, ndi mitundu yochepa chabe ya maselo yomwe ingatchulidwe nthawi imodzi. Mosiyana ndi izi, kuwala kocheperako kwa bandi ya microdisk laser kudzatha kuzindikira mitundu yambiri yama cell nthawi imodzi.
Gululo linayesa ndikuwonetsa bwino tinthu tating'onoting'ono ta laser tating'onoting'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono ta MCF10A. Ndi ma Ultra-wideband amatulutsa, ma lasers amatha kusintha kusintha kwa biosensing, pogwiritsa ntchito njira zotsimikiziridwa za biomedical ndi kuwala monga cytodynamic imaging, flow cytometry, ndi multi-omics kusanthula. Ukadaulo wozikidwa pa PEC etching ukuwonetsa kupita patsogolo kwakukulu mu ma lasers a microdisk. Kuchuluka kwa njirayo, komanso kulondola kwake kwa subnanometer, kumatsegula mwayi watsopano wogwiritsa ntchito ma lasers mu nanophotonics ndi zida za biomedical, komanso ma barcode a ma cell angapo ndi ma molekyulu owunikira.
Nthawi yotumiza: Jan-29-2024